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Table 2 Frequency of the investigated cell surface and intracellular markers

From: B7 costimulation and intracellular indoleamine-2,3-dioxygenase (IDO) expression in peripheral blood of healthy pregnant and non-pregnant women

  Non-pregnant women (n = 14) Healthy pregnant women (n = 20)
CD3+ CD28+ cells/CD3+ lymphocytes 76.0 (64.7-82.9)% 88.4* (81.8-90.6)%
CD3+ CD28+ CD152+ cells/CD3+ CD28+ lymphocytes 8.90 (7.57-11.4)% 6.64* (5.07-9.89)%
CD3+ CD278+ cells/CD3+ lymphocytes 55.7 (49.5-56.7)% 89.9* (75.7-91.6)%
CD3+ CD279+ cells/CD3+ lymphocytes 46.3 (39.3-51.2)% 51.9* (47.9-67.7)%
CD4+ CD28+ cells/CD4+ lymphocytes 97.8 (96.7-98.8)% 97.3 (93.0-99.2)%
CD4+ CD28+ CD152+ cells/CD4+ CD28+ lymphocytes 6.92 (4.93-8.63)% 5.61 (3.65-9.09)%
CD4+ CD278+ cells/CD4+ lymphocytes 56.7 (52.8-59.5)% 87.7* (76.3-92.2)%
CD4+ CD279+ cells/CD4+ lymphocytes 49.4 (42.1-54.5)% 44.2 (37.5-65.2)%
CD11b + CD80+ cells/CD11b + monocytes 55.5 (17.3-69.8)% 17.6* (13.6-25.4)%
CD11b + CD86+ cells/CD11b + monocytes 23.8 (17.3-29.5)% 20.7 (14.9-31.9)%
CD11b + CD274+ cells/CD11b + monocytes 78.4 (70.3-85.9)% 80.7 (77.2-87.8)%
CD11b + CD275+ cells/CD11b + monocytes 63.8 (59.0-72.1)% 17.3* (14.1-27.0)%
CD3+ IDO + cells/CD3+ lymphocytes 5.90 (2.65-16.9)% 24.1* (13.3-56.4)%
IDO mean fluorescence intensity in CD3+ IDO + cells (arbitrary unit) 9888 (7482–11475) 62500* (19800–84475)
CD11b + IDO + cells/CD11b + monocytes 2.59 (1.99-11.7)% 22.5* (13.6-50.5)%
IDO mean fluorescence intensity in CD11b + IDO + cells (arbitrary unit) 21400 (19075–23875) 70450* (38775–114000)
  1. *p < 0.05 versus non-pregnant women. Data are presented as median (interquartile range). IDO – indoleamine-2,3-dioxygenase, MFI – mean fluorescence intensity.