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Table 1 Identification and localization of genotyped SNPs and set of primers designed for sequencing

From: Ancestry informative markers and selected single nucleotide polymorphisms in immunoregulatory genes on preterm labor and preterm premature rupture of membranes: a case control study

Gene Location Variable sites (a) SNP locationb Primers
IL1B 2q14 rs1143627 (−31 T > C) 112836810 IL1b31 F 5’-CCCCTAAGAAGCTTCCACCA- 3’
IL1b31 R 5’-AAGAGAATCCCAGAGCAGCC- 3’
rs16944 (−511 C > T) 112837290 IL1b511 F 5’-TGAGGGTGTGGGTCTCTACC- 3’
IL1b511 R 5’-TGGCTAGGGTAACAGCACCT- 3’
IL6 7p21 rs1800795 (−174 G > C) 22727026 IL6 F 5’-TGCACTTTTCCCCCTAGTTG- 3’
IL6 R 5’-GCCTCAGACATCTCCAGTCC- 3’
IL6R 1q21.3 rs2228144 154429203 IL6R1 F 5’-GAGAATGCTGCCCTAATCCA- 3’
IL6R1 R 5’-GCATTGTCTTCCGGCTCTAC- 3’
rs2228145 (D358A A > C) 154454494 IL6R2 F 5’-GAGGGGAAGGTTCCTTTGAG- 3’
IL6R2 R 5’-GAACACCACAGGGCCATC- 3’
TNFA 6p21.3 rs361525 (−238 G > A) 31575324 TNF238 F 5’-AATCAGTCAGTGGCCCAGAA- 3’
TNF238 R 5’-ATCTGGAGGAAGCGGTAGTG- 3’
rs1800629 (−308 G > A) 31575254 TNF308 F 5’-GAAGCCCCTCCCAGTTCTAG- 3’
TNF308 R 5’-TCTGGGCCACTGACTGATTT- 3’
TNFRII 1p36.3 rs653667 (−24660) 12191751 TNFR 5’-F 5’-GAGTGCAGGCTTGAGTTTCC- 3’
TNFR 5’-R 5’-GTGTTGTGTGTGCCCCATG- 3’
IL10 1q31-32 rs1800872 (−592 C > A) 206773062 IL10-592 F 5’-TGGAAACATGTGCCTGAGAA- 3’
IL10-592R 5’-GAGGGGGTGGGCTAAATATC- 3’
rs1800871 (−819 G > A) 206773289 IL10-819 F 5’-TGGTGTACAGTAGGGTGAGG- 3’
IL10-819 R 5’-GGGAAGTGGGTAAGAGTAGTC- 3’
rs1800896 (−1082 A > G) 206773552 IL10-1082 F 5’-CAACTGGCTCCCCTTACCTT- 3’
IL10-1082 R 5’-ATGGAGGCTGGATAGGAGGT- 3’
TLR2 4q32 rs4696480 153685974 TLR2 F 5’-CTTGGGTGCTGCTGTAACAA- 3’
TLR2 R 5’-TGTTATCACCAAGGGAGCAG- 3’
TLR4 9q32-33 rs4986790 (Asp299Gly) 117713024 TLR4-299 F 5’-CTCTAGAGGGCCTGTGCAAT- 3’
TLR4-299 R 5’-TCAATGTGGGAAACTGTCCA- 3’
rs4986791 (Thr399Ile) 117713324 TLR4-399 F 5’-CAACAAAGGTGGGAATGCTT- 3’
TLR4-399 R 5’-TCAAATTGGAATGCTGGAAA- 3’
TIMP1 Xp11.3 rs2070584 47587120 TIMP1 F 5’-CAACAGCAGCAATGGTCACT- 3’
TIMP1 R 5’-CTGGCAAGATGTGTGAATGG- 3’
TIMP2 17q25 rs2277698 78870935 TIMP2 F 5’-TCCTCCTCCTTGTCTTTCCA- 3’
TIMP2 R 5’-TAGGAACAGCCCCACTTCTG- 3’
MMP9 20q11.2-13.1 rs3918242 (−1562C > T) 46007337 MMP9 F 5’-5’- GCCTGGCACATAGTAGGCCC-3’
MMP9 R 5’-5’- CTTCCTAGCCAGCCGGCATC-3’
  1. aAs commonly referred in the literature. bObtained from dbSNP (NCBI)