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Table 4 Knowledge test - respondents were asked to choose if each statement was true, false or if they were unsure

From: Development and evaluation of training resources to prepare health professionals for counselling pregnant women about non-invasive prenatal testing for Down syndrome: a mixed methods study

Knowledge test statement Correct answer Pre-training results 1-month follow-up after training results
   Correct Incorrect/unsure Correct Incorrect/unsure
Cell free fetal DNA originates from cells in the placenta True 37 (25.3%) 109 (74.7%) 88 (63.8%) 50 (36.2%)
The concentration of cell free fetal DNA decreases with gestation False 23 (15.6%) 124 (84.4%) 88 (42%) 80 (58%)
NIPT measures chromosome levels to identify elevated levels of chromosome 21, 18 and 13 True 57 (38.5%) 91 (61.5%) 113 (81.9%) 25 (18.1%)
NIPT for Down’s syndrome is over 99% accurate True 72 (48.6%) 76 (51.4%) 98 (71%) 40 (29%)
The false positive rate for NIPT for Down’s syndrome is 10% False 28 (19%) 119 (81%) 88 (63.8%) 50 (36.2%)
The turnaround time for the NIPT test is three weeks False 25 (16.9%) 123 (83.1%) 54 (39.4%) 83 (60.6%)
NIPT for Down’s syndrome is being offered on a research basis to everyone with a screening test risk higher than 1:1000 True 52 (35.1%) 96 (64.9%) 109 (79%) 29 (21%)
There are three possible NIPT results: positive, negative or inconclusive True 69 (46.6%) 79 (53.4%) 126 (91.3%) 12 (8.7%)
Women who receive a positive NIPT result will be offered an invasive test to confirm the result True 65 (43.9%) 83 (56.1%) 129 (93.5%) 9 (6.5%)