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Table 3 Sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV)

From: Development of a melting-curve based multiplex real-time PCR assay for simultaneous detection of Streptococcus agalactiae and genes encoding resistance to macrolides and lincosamides

Multiplex real-time PCR Culturea Total
  Positive Negative  
Positive 11 4 15
Negative 1 86 87
Total 12 90 102
Sensitivity (95% CI)b 91.7% (59.7–99.5%)
Specificity (95% CI)b 95.5% (88.4–98.6%)
PPV (95% CI)b 73.3% (44.8–91.1%)
NPV (95% CI)b 98.9% (92.9–99.9%)
  1. aStandard routine culture of vaginal-rectal swab specimen collected from pregnant women at 35–37 weeks of gestation; bValues calculated with 95% confidence interval (CI) using the program available at http://faculty.vassar.edu/lowry/clin1.html