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Table 1 Characteristics of the study population according to amniotic fluid culture results

From: Plasma inflammatory and immune proteins as predictors of intra-amniotic infection and spontaneous preterm delivery in women with preterm labor: a retrospective study

  Amniotic fluid culture P-value
Positive (n = 16) Negative (n = 157)
Maternal age (years) 31.3 ± 4.9 31.6 ± 4.0 0.638
Nulliparity 56% (9) 62% (97) 0.666
Gestational age at sampling (weeks) 28.3 ± 3.0 30.2 ± 2.6 0.014
Gestational age at delivery (weeks) 30.0 ± 3.1 35.9 ± 3.5 < 0.001
Serum C-reactive protein (mg/L) 25.3 ± 21.5 7.5 ± 11.6 < 0.001
Cervical length on ultrasonography (mm) 19.2 ± 8.9 25.3 ± 12.1 0.054
Plasma C3a (μg/mL) 13.8 ± 6.8 12.8 ± 7.9 0.366
Plasma C5a (ng/mL) 46.0 ± 10.3 44.8 ± 13.0 0.712
Plasma interleukin-6 (pg/mL) 9.9 ± 9.3 4.6 ± 6.1 0.001
Plasma matrix metalloproteinase-9 (ng/ml) 248.7 ± 232.0 210.6 ± 185.0 0.405
Use of tocolytic agents 94% (15) 94% (147) 0.985
Use of antibiotics 75% (12) 26% (40) < 0.001
Use of antenatal corticosteroids 100% (17) 75% (120) 0.026
Clinical chorioamnionitis 6% (1) 0% (0) 0.002
Histological chorioamnionitisa 75% (12/16) 32% (27/85) 0.001
Amniotic fluid interleukin-6 (ng/mL) 26.3 ± 21.4 1.9 ± 7.7 < 0.001
  1. Data are given as mean ± standard deviation or % (n/N)
  2. aData for the histologic evaluation of the placenta were only available for 101 of the 173 women because delivery took place at another institution in 5 cases, and histologic evaluation of the placenta was not performed in 67 cases because of our institutional policy that only the placentas from preterm deliveries are sent for histopathologic examination