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Table 2 Birth related factors of babies of women in the Cambridge Baby Growth Study who returned their questionnaires, categorised according to whether they experienced nausea or vomiting in pregnancy

From: Vomiting in pregnancy is associated with a higher risk of low birth weight: a cohort study

Birth-related Factor No Nausea or Vomiting Nausea alone Vomiting
n 286 467 465
Parity (n) 1.7 (1.6-1.8) 1.8 (1.7-1.8) 1.8* (1.8-1.9)
Birth weight (kg) 3.512 (3.459, 3.565) 3.504 (3.474, 3.534) 3.496 (3.453, 3.540)
Adjusted birth weight (kg) 3.494 (3.449, 3.539) 3.499 (3.474, 3.525) 3.505 (3.468, 3.541)
LBW (n/total (%)) 6/277 (2.2%) 9/461 (2.0%) 21/460* (4.6%)
LBW (OR) Ref. 1.0 (0.3-4.0) 3.5* (1.2-10.8)
LBW (OR) first trimester nausea or vomiting 2.1 (0.8-5.7) 4.3* (1.4-13.2)
LBW (OR) second trimester nausea or vomiting 4.2* (1.7-10.1) 4.4* (1.4-13.9)
LBW (OR) third trimester nausea or vomiting 1.5 (0.3-6.7) 0.8 (0.1-7.0)
Gestational age at birth (weeks) 39.9 (39.8, 40.1) 39.9 (39.8, 40.0) 39.8 (39.7, 39.9)
Prematurity (n (%)) 4 (1.4) 7 (1.5) 11 (2.3)
SGA (n (%)) 11 (3.9) 16 (3.5) 25 (5.2)
Sex of the baby (n (%) male) 161 (56.9%) 236 (51.1%) 225 (49.9%)*
  1. *P < 0.05, **P < 0.01, ***P < 0.001 compared with the no nausea or vomiting group. None of these women were treated with anti-emetics during pregnancy. Nausea alone refers to those women who experienced nausea in pregnancy but not vomiting. Vomiting refers to those women who experienced vomiting during pregnancy, independently of whether or not they also experienced nausea. Birth weight is presented both unadjusted and adjusted for pre-pregnancy maternal BMI, gestational age at birth, parity, multi-fetal pregnancy and sex. LBW OR was adjusted for parity, marital status, ethnicity and maternal smoking status. Data are mean (95% CI) or number (%)