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Table 2 Univariable analysis of risk factors for hysterectomy in women with postpartum haemorrhage

From: Risk factors for peripartum hysterectomy among women with postpartum haemorrhage: analysis of data from the WOMAN trial

Variable Total n(%) of women who had hysterectomy Age-adjusted odds ratio (95% CI)a P-value†
Cause of haemorrhage
 Uterine atony 12,759 421 (3.3) 1 < 0.001
 Surgical trauma/tears 3681 181 (4.9) 1.49 (1.24–1.80)  
 Placenta praevia/accreta 1874 326 (17.4) 4.87 (4.11–5.77)  
 Other/Unknown 1699 90 (5.3) 1.40 (1.10–1.80)  
Age (years)
 < 20 1021 12 (1.2) 1 < 0.001
 20–29 10,408 306 (2.9) 2.15 (1.20–3.86) < 0.001ǂ
 30–39 7900 615 (7.8) 5.98 (3.34–10.70)  
 ≥40 681 87 (12.8) 11.73 (6.30–21.85)  
Geographic region
 Africa 12,714 570 (4.5) 1 < 0.001
 Asia 6173 420 (6.8) 1.67 (1.20–2.34)  
 Europe and Americas 1130 30 (2.7) 0.53 (0.26–1.08)  
Delivery in study hospital
 Yes 17,586 868 (4.9) 1 0.77
 No 2428 152 (6.3) 0.97 (0.80–1.18)  
Uterotonic prophylaxis given
 Yes 19,264 940 (4.9) 1 < 0.001
 No 269 40(14.9) 2.65 (1.80–3.88)  
Type of delivery
 Vaginal 14,188 357 (2.5) 1 < 0.001
 Caesarean 5824 661 (11.4) 4.50 (3.89–5.21)  
Full delivery of placenta
 Yes 18, 064 796 (4.4) 1 < 0.001
 No 1950 223 (11.4) 2.24 (1.89–2.66)  
Systolic blood pressure (mmHg)
 ≤70 1532 210 (13.7) 6.40 (5.25–7.81) < 0.001
 71–90 5925 453 (7.7) 3.02 (2.59–3.53) < 0.001ǂ
 > 90 12,555 357 (2.8) 1  
Estimated volume of blood loss (mL)
 ≤ 1000 10,400 86 (0.8) 1 < 0.001
 1001–1500 5703 238 (4.2) 5.35 (4.13–6.93) < 0.001ǂ
 > 1500 3911 696 (17.8) 32.02 (24.97–41.05)  
Clinical signs of haemodynamic instability
 No 8194 128 (1.6) 1 < 0.001
 Yes 11,822 891 (7.5) 7.35 (5.96–9.06)  
  1. aCI, confidence interval
  2. P-values obtained from likelihood ratio test
  3. ǂLikelihood ratio test for linear trend