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Table 1 Unadjusted values for vascular measures and biomarkers by trimester and postpartum

From: Common carotid artery intima-media thickness increases throughout the pregnancy cycle: a prospective cohort study

Measure 1st trimester n = 17 2nd trimester n = 32 3rd trimester n = 37 1st postpartum n = 35 2nd postpartum n = 14 Overall P-value
Inter-adventitial diameter (mm) 6.47 (0.12) 6.79 (0.08) 6.89 (0.10) 6.36 (0.07) 6.42 (0.11) <  0.0001
CCA intima-media thickness (mm) 0.547 (0.02) 0.546 (0.01) 0.553 (0.01) 0.565 (0.01) 0.581 (0.02) 0.03
Weight (kg) 68.7 (2.2) 73.1 (1.6) 79.5 (1.8) 69.2 (1.5) 70.2 (1.9) <  0.0001
Weight change (kg) 0.55 (0.46) 7.27 (0.62) 14.4 (0.91) 4.3 (0.75) 3.7 (1.1) <  0.0001
Systolic blood pressure (mm Hg) 103.7 (2.1) 106.0 (1.7) 110.4 (1.4) 106.2 (1.7) 102.9 (2.5) <  0.0001
Heart rate (bpm) 78.0 (2.4) 79.8 (1.6) 82.0 (1.5) 68.1 (1.5) 63.6 (2.5) <  0.0001
Total cholesterol (mg/dl) 201.7 (8.9) 257.3 (7.0) 273.1 (7.2) 191.4 (5.5) 194.8 (8.4) <  0.0001
LDL-c (mg/dl) 111.2 (7.0) 148.0 (6.3) 155.5 (6.6) 114.7 (4.8) 121.9 (7.0) <  0.0001
Triglycerides (mg/dl) 108.3 (10.5) 176.5 (10.2) 250.7 (13.6) 77.3 (7.0) 87.1 (9.6) <  0.0001
HDL-c (mg/dl) 68.8 (2.2) 74.0 (3.1) 66.8 (2.3) 61.2 (1.8) 55.6 (2.9) <  0.0001
Glucose (mg/dl) 79.3 (1.5) 77.2 (1.1) 77.0 (1.2) 82.6 (1.2) 88.5 (1.9) <  0.0001
Insulin (μU/ml) 8.84 (0.78) 11.25 (0.98) 11.95 (0.81) 8.59 (0.50) 10.76 (0.82) 0.0008
HOMA-IR 1.64 [1.32, 2.09] 2.16 [1.56, 2.56] 2.28 [1.67, 2.51] 1.72 [1.34, 2.13] 2.20 [1.76, 2.87] 0.03
hsCRP (mg/L) 3.58 [2.16, 5.57] 3.36 [2.31, 5.49] 3.29 [2.24, 7.01] 1.20 [.77, 2.44] 0.96 [0.37, 1.50] <  0.0001
  1. Normally distributed values presented as mean (SE) and P value from mixed models. Skewed values presented as median [IQR] and P-value from Wilcoxon rank-sum test. CCA is common carotid artery. Weight change is change from pre-pregnancy weight