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Table 2 Associationsa between inter-adventitial diameter, physical predictors, and significant metabolic predictors

From: Common carotid artery intima-media thickness increases throughout the pregnancy cycle: a prospective cohort study

Predictor Unadjusted Model 1b Model 2b
  ß (SE) P-value ß (SE) P-value ß (SE) P-value
Trimester 1 Ref   Ref   Ref  
Trimester 2 0.361 (.07)c 0.0001 0.361 (.07)c < 0.0001 0.389 (.07)c < 0.001
Trimester 3 0.498 (.07)cd 0.0001 0.499 (.07)cd < 0.0001 0.511 (.07)c < 0.001
Postpartum −0.015 (.05) 0.74 −0.014 (.05) 0.76 0.010 (.04) 0.81
Age (years)    −0.004 (.02) 0.81 −0.003 (.02) 0.83
Pre-pregnancy BMI (kg/m2)    0.046 (.02) 0.06 0.042 (.02) 0.09
SBP (mmHG)      0.004 (.00) 0.29
Predictor Model 3b Model 4b Model 5b
  ß (SE) P-value ß (SE) P-value ß (SE) P-value
Trimester 1 Ref   Ref 0.84 Ref  
Trimester 2 0.294 (.09)c 0.001 0.321 (.09)c < 0.001 0.456 (.07)c < 0.0001
Trimester 3 0.338 (.13)c 0.009 0.392 (.14)c 0.008 0.683 (.12)cd < 0.0001
Postpartum −0.032 (.05) 0.49 −0.020 (.05) 0.69 − 0.029 (.04) 0.44
Age (years) 0.004 (.02) 0.82 − 0.001 (.02) 0.93 −0.006 (.02) 0.73
Pre-pregnancy BMI (kg/m2) 0.013 (.03) 0.67 0.047 (.02) 0.06 0.006 (.03) 0.85
Weight (kg) 0.015 (.01) 0.08    0.011 (.01) 0.12
Weight change (kg)    0.010 (.01) 0.29   
Triglycerides (mg/dl)      −0.002 (.00) < 0.0001
Log hsCRP (mg/L)      0.070 (.02) 0.0002
  1. aLinear mixed models
  2. bModel 1: Adjusted for age & pre-pregnancy BMI. Model 2: Model 1 plus SBP. Model 3: Model 1 plus weight. Model 4: Model 1 plus weight change. Model 5: Model 3 plus triglycerides and Log hsCRP
  3. cDifferent from postpartum at p < .01. dDifferent from second trimester at p < .05
  4. Weight change is from pre-pregnancy weight. β represents change in millimeters