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Table 2 The components of the metabolic syndrome (MetS) in the study subjects at the follow-up study stratified according to the offspring’s birth weight

From: Future risk of metabolic syndrome in women with a previous LGA delivery stratified by gestational glucose tolerance: a prospective cohort study

Offspring’s birth weight AGA (10-90th percentile) LGA (>90th percentile)
Mean ± SD or % Mean ± SD or %
No GDM GDM No GDM GDM
(Controls) (Group 1) (Group 2) (Group 3)
Number of subjects 286 376 48 68
Waist circumference (cm) 85.3 ± 11.6 91.0 ± 13.8** 88.8 ± 10.8* 94.2 ± 12.9**
Waist circumference ≥ 80 cm (%) 64.0 77.6** 81.3* 89.7**
Fasting glucose (mmol/l) 5.3 ± 0.4 5.6 ± 0.8** 5.4 ± 0.4 5.8 ± 0.8**
Fasting glucose ≥5.6 mmol/l (%) 25.2 46.8** 29.2 58.8**
Triglycerides (mmol/l) 1.0 ± 0.6 1.1 ± 0.6* 0.9 ± 0.4 1.2 ± 0.5*
Triglycerides ≥1,70 mmol/l (%) 10.6 15.2 4.2 16.2
HDL cholestrol (mmol/l) 1.5 ± 0.4 1.4 ± 0.4** 1.6 ± 0.3 1.3 ± 0.3**
HDL cholestrol < 1.29 mmol/l (%) 28.3 44.1** 20.8 57.4**
Systolic pressure (mmHg) 122.5 ± 14.3 125.8 ± 14.1* 121.4 ± 10.1 128.4 ± 14.2*
Diastolic pressure (mmHg) 78.3 ± 9.6 79.3 ± 9.2 77.5 ± 7.5 81.3 ± 10.0*
Blood pressure ≥ 130/≥85 mmHg (%) 34.3 38.8 27.1 45.6
Metabolic syndrome (IDF) (%) 24.5 43.6** 18.8 54.4**
  1. GDM gestational diabetes mellitus, BMI body mass index, AGA appropriate for gestational age, LGA large for gestational age
  2. All groups compared to controls separately
  3. *p < 0.05
  4. **p < .0001