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Table 2 sFlt-1, PlGF and sFlt-1:PlGF ratios compared between controls and: (i) cases with a SGA infant; (ii) preeclampsia cases

From: Assessing the sensitivity of placental growth factor and soluble fms-like tyrosine kinase 1 at 36 weeks’ gestation to predict small-for-gestational-age infants or late-onset preeclampsia: a prospective nested case-control study

  Controls All SGA P SGA only P Preeclampsia P
sFlt-1 (pg/ml) 2446 [1795–3503] 2837 [1850–4250] 0.02 2620 [1835–4099] 0.10 4857 [3777–6941] < 0.001
PlGF (pg/ml) 326.7 [173.1–675.4] 178.5 [106.4–404.8] < 0.001 199.9 [118.1–448.6] < 0.001 99.73 [61.99–158.6] < 0.001
sFlt-1:PlGF ratio 7.11 [3.08–15.58] 14.24 [6.00–37.37] < 0.001 13.00 [5.27–32.44] < 0.001 54.25 [26.81–114.5] < 0.001
  1. Data presented as median [25th–75th percentile]. “All SGA” = Cases with a SGA fetuses including cases with co-existent preeclampsia; “SGA only” = Cases with SGA fetuses with cases of co-existant preeclampisa excluded; pg/ml = picogram/millilitre, PlGF placental growth factor, sFlt-1 soluble fms-like tyrosine kinase-1, SGA small-for-gestational-age (birthweight <10th centile). For sFlt-1 and sFlt-1:PlGF ratio results n = 207 for controls, n = 102 for ‘All SGA’, n = 39 for ‘Preeclampsia’. For PlGF results n = 210 for controls, n = 104 for ‘All SGA’, and n = 39 for ‘Preeclampsia’