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Table 4 Diagnostic performance of sFlt-1:PlGF ratio ≥ 38 for preeclampsia, and < 10th and < 3rd centile infants

From: Assessing the sensitivity of placental growth factor and soluble fms-like tyrosine kinase 1 at 36 weeks’ gestation to predict small-for-gestational-age infants or late-onset preeclampsia: a prospective nested case-control study

Outcome Sensitivity Specificity PPV NPV
Preeclampsia 66.7% [49.8–80.9%] 94.2% [90.1–97.0%] 31.8% [20.5–45.8%] 98.6% [97.8–99.1%]
Birthweight < 10th centile (All SGA) 24.5% [16.5–34.0%] 94.2% [90.1–97.0%] 32.4% [20.1–47.8%] 91.7% [90.7–92.5%]
Birthweight < 3rd centile (All SGA) 25.0% [10.7–44.9%] 89.3% [85.1–92.7%] 6.3% [3.2–12.3%] 97.6% [97.1–98.1%]
  1. Data presented with [95% Confidence Interval]. NPV Negative Predictive value, PlGF placental growth factor, PPV Positive Predictive Value, sFlt-1 soluble fms-like tyrosine kinase-1, SGA small-for-gestational-age